What happens when a good for nothing-handsome hunk Mac (Akshay Kumar) finds himself in possession of an empty flat and access to three gorgeous air hostesses Dipti (Daisy Bopanna), Sweety (Neetu Chandra) and Puja (Nargis Bagheri)? Garam Masala! What happens when Mac who is already engaged to Anjali (Rimi Sen), convinces each of the three girls that she is the only one for him? Garam Masala! What happens when Sam (John Abraham), once Mac's best friend now sworn enemy, threatens to reveal Mac harem to Anjali? What happens when all the girls land in the flat at the same time? Garam Masala!